immunologyLikely exemptAnnex III — Jul 31 2026

Enbrel Tariff Rate & July 31, 2026 Deadline

Enbrel (Etanercept) — manufactured by Amgen in Puerto Rico (US). Treats rheumatoid arthritis, psoriasis. Typical US retail $7,100 per month.

Tariff breakdown

Applicable rate: 100% (Annex III)
Effective date: 2026-07-31 (98 days away)
Manufacturer: Amgen
Country of origin: Puerto Rico (US)
Annex III?: Yes
Current monthly retail: $7,100

Why Enbrel is likely exempt: Manufactured in Puerto Rico (US territory)

HTS classification

HTS 3002.15.0000

Etanercept fusion-protein biologic, HTS 3002.15. Amgen manufactures Enbrel in Puerto Rico (US territory) — exempt in practice.

Source: USITC Harmonized Tariff Schedule, 2026 Revision 2 — hts.usitc.gov

Alternatives: generics, biosimilars & US-made options

Etanercept biosimilars (Erelzi, Eticovo)

biosimilar

FDA-approved but commercial launch in the US has been blocked by patent litigation through 2029 — not practically available yet.

Humira (adalimumab, AbbVie)

us made

Alternative TNF inhibitor; AbbVie produces Humira in Puerto Rico — also tariff-exempt.

Always consult your prescriber before switching medications. Biosimilars and generics are not interchangeable in every state without physician approval.

FAQ: Enbrel and the 2026 tariff

Will my Enbrel prescription cost more after July 31, 2026?

Probably not directly — Enbrel is classified as exempt because Manufactured in Puerto Rico (US territory). The tariff itself should not raise your list price, though PBM renegotiations and formulary changes can still move your copay.

Can I switch to a generic version of Etanercept?

No FDA-approved generic of Etanercept is widely available in the US as of 2026 Q2. Biosimilars or therapeutic alternatives (listed above) are the practical substitutes.

Is Enbrel on the Medicare negotiated-price list?

Enbrel is not among the first-round Medicare-negotiated drugs effective 2026. Check CMS announcements for subsequent negotiation rounds.

Importing pharmaceuticals commercially?

This page covers consumer drug pricing. For business imports (including finished-dose pharmaceuticals), use the full US import tariff calculator with HTS classification and Section 301/232/122 breakdown.

Disclaimer: Informational estimates based on public list prices, the April 2, 2026 Proclamation text, and USITC HTS data. Not medical, legal, or financial advice.

Talk to your doctor, pharmacist, and insurer about your specific medication.